[Morphological and functional studies on the secretory mechanism of the thyroid stimulating hormone].

Koji KIDO Department of Obstetrics & Gynecology, Kobe Medical College (Director : Prof. Yasuo Ueda) On the subject of the secretory mechanism of the thyroid stimulating hormone in the anterior pituitary, there still remains a number of unsolved problems. To clarify one of the aspects, the author has attempted an investigation of TSH content in the pituitary gland which was assayed by the modified Greenspan method and histochemical studies of the pituitary under the various experimental conditions in female rats. The results are summarized as follows : A) Radiothyroidectomized female rats. 1) The anterior pituitary gland showed remarkable hypertrophy after the radiothyroidectomy and TSH content of the pituitary of the radiothyroidectomized rat was as shown in Table 1.